Reinhold P
Berl Munch Tierarztl Wochenschr. 1997 Jul-Aug;110(7-8):257-66.
The analysis of respiratory mechanics using the forced oscillation technique (FOT) was originally developed for human medicine. Since this technique can be used during spontaneous breathing and does not require patient cooperation, it is generally applicable to conscious animals. In contrast to conventional methods to characterise the mechanics of breathing, FOT has the advantage of being non-invasive. Compared to the classical method which takes mechanical parameters (resistance, inertance, compliance) into account, the forced oscillation techniques utilises electrical parameters (resistance, inductance, capacitance). Briefly, in the forced oscillation technique, externally generated test signals are sent to the respiratory system under investigation. These test signals are superimposed on spontaneous breathing. In order to examine respiratory mechanics, the response of the respiratory system to these test signals is analysed and interpreted. The complex respiratory impedance resulting from this analysis contains information concerning the resistive, capacitive and inductive properties of the respiratory system. In general, FOT is a portable technique which can be applied to several kinds of animals.
使用强迫振荡技术(FOT)分析呼吸力学最初是为人类医学开发的。由于该技术可在自主呼吸期间使用且无需患者配合,因此通常适用于清醒动物。与传统的表征呼吸力学的方法相比,FOT具有非侵入性的优点。与考虑机械参数(阻力、惯性、顺应性)的经典方法相比,强迫振荡技术利用电参数(电阻、电感、电容)。简而言之,在强迫振荡技术中,外部产生的测试信号被发送到所研究的呼吸系统。这些测试信号叠加在自主呼吸上。为了检查呼吸力学,分析并解释呼吸系统对这些测试信号的响应。由此分析得出的复呼吸阻抗包含有关呼吸系统电阻、电容和电感特性的信息。一般来说,FOT是一种便携式技术,可应用于多种动物。