Adamopoulos G, Yotakis I, Apostolopoulos K, Manolopoulos L, Kandiloros D, Ferekidis E
Ear, Nose and Throat Department, Faculty of Medicine, University of Athens, Greece.
J Laryngol Otol. 1997 Aug;111(8):730-4.
Between October 1987 and October 1993, 92 patients with squamous cell carcinoma of the supraglottis were treated by supraglottic laryngectomy and neck dissection in our department. There were 33 T1, 46 T2, six T3 and seven T4 cases. All patients with N+ necks and T3 or T4 tumours received post-operative radiotherapy (5,000-6,500 cGy). The patients were followed for a minimum of 36 months or until death. The incidence of local recurrence was 7.6 per cent. Neck recurrence was observed in 13 per cent of patients. Decannulation was achieved in 93.4 per cent of the cases with three patients undergoing gastrostomy because of aspiration. The average hospital stay was 26 days. The overall three-year survival was 83.6 per cent, with eight patients dying of unrelated causes. There was a significant difference in recurrence rate between patients in the N0 and the N+ stage.
1987年10月至1993年10月期间,我科对92例声门上型鳞状细胞癌患者实施了声门上喉切除术及颈部清扫术。其中T1期33例,T2期46例,T3期6例,T4期7例。所有N+颈部及T3或T4肿瘤患者均接受术后放疗(5000 - 6500 cGy)。对患者进行了至少36个月的随访或直至死亡。局部复发率为7.6%。13%的患者出现颈部复发。93.4%的病例实现了拔管,3例患者因误吸接受了胃造瘘术。平均住院时间为26天。三年总生存率为83.6%,8例患者死于无关原因。N0期和N+期患者的复发率存在显著差异。