Miyaguchi M, Takashima H, Kubo T
Department of Otorhinolaryngology, Osaka University School of Medicine, Japan.
J Laryngol Otol. 1997 Aug;111(8):763-5. doi: 10.1017/s0022215100138563.
Post-radiation necrosis of the larynx is a major complication after irradiation and has become rare. Recently, combined chemotherapy and radiation therapy has been introduced for head and neck tumours. The authors report a case of laryngeal necrosis after combination therapy for a patient with cervical lymph node metastases of nasopharyngeal carcinoma and review the literature on late laryngeal necrosis. Although radiation-induced laryngeal necrosis has become a rare complication, the combination of chemotherapy and radiation therapy may increase its incidence. We should always consider it as a possible late complication and treat it appropriately.
喉放射性坏死是放疗后的一种主要并发症，现已较为罕见。近年来，头颈部肿瘤引入了化疗联合放疗的治疗方法。作者报告了1例鼻咽癌颈部淋巴结转移患者在联合治疗后发生喉坏死的病例，并对有关晚期喉坏死的文献进行了综述。尽管放射性喉坏死已成为一种罕见的并发症，但化疗与放疗联合可能会增加其发生率。我们应始终将其视为一种可能的晚期并发症并进行适当治疗。
