Laryngeal chondroradionecrosis following radiotherapy.
作者信息
Melo Giulianno Molina, Souza Paula Demetrio, Bastos Luiz Castro, Neves Murilo Catafesta, Espirito Santo Kleber Simões do, Cervantes Onivaldo, Abrahão Márcio
机构信息
Universidade Federal de São Paulo, Disciplina de Cirurgia de Cabeça e Pescoço, Departamento de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, São Paulo, SP, Brasil.
Hospital da Beneficência Portuguesa de São Paulo, Serviço de Cirurgia de Cabeça e Pescoço, São Paulo, SP, Brasil.
出版信息
Rev Col Bras Cir. 2017 Jul-Aug;44(4):374-382. doi: 10.1590/0100-69912017004012.
OBJECTIVE
to study larynx chondroradionecrosis related to radiotherapy and chemotherapy treatment and provide a treatment flowchart.
METHODS
retrospective study with clinical data analysis of all larynx cancer patients admitted in a two tertiary hospital in a five years period.
RESULTS
from 131 patients treated for larynx cancer, 28 underwent chemoradiotherapy with curative intent and three of them presented chondroradionecrosis. They were treated with hiperbaric oxigen therapy and surgical debridment following our flowchart, preserving the larynx in all.
CONCLUSIONS
the incidence of chondroradionecrosis as a complication of chemoradiotherapy in our series was 10,7% and the treatment with hiperbaric oxigen therapy, based in our flowchart, was effective to control this complication.
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