Guille M J, Kneale G G
Division of Molecular and Cell Biology, School of Biological Science, University of Portsmouth, UK.
Mol Biotechnol. 1997 Aug;8(1):35-52. doi: 10.1007/BF02762338.
The interaction of proteins with DNA is a central theme of molecular biology. In this article, we review some of the principal techniques currently used for the identification and characterization of DNA binding proteins, and for investigation of the molecular interactions that are responsible for the recognition of specific DNA sequences.
蛋白质与DNA的相互作用是分子生物学的核心主题。在本文中,我们综述了目前用于鉴定和表征DNA结合蛋白,以及研究负责识别特定DNA序列的分子相互作用的一些主要技术。