Is L-DOPA a neurotransmitter of the primary baroreceptor afferents terminating in the nucleus tractus solitarii of rats? - Suppr | 超能文献

Is L-DOPA a neurotransmitter of the primary baroreceptor afferents terminating in the nucleus tractus solitarii of rats?

作者信息

Misu Y, Goshima Y, Yue J L, Miyamae T

机构信息

Department of Pharmacology, Yokohama City University School of Medicine, Japan.

出版信息

Adv Pharmacol. 1998;42:855-8. doi: 10.1016/s1054-3589(08)60881-9.

DOI:10.1016/s1054-3589(08)60881-9

Abstract

摘要

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Is L-DOPA a neurotransmitter of the primary baroreceptor afferents terminating in the nucleus tractus solitarii of rats?

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GABA may function tonically via GABA(A) receptors to inhibit hypotension and bradycardia by L-DOPA microinjected into depressor sites of the nucleus tractus solitarii in anesthetized rats.在麻醉大鼠中，γ-氨基丁酸（GABA）可能通过GABA（A）受体发挥紧张性作用，以抑制左旋多巴微量注射到孤束核减压部位所引起的低血压和心动过缓。

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