因茚地那韦结晶尿症和肾结石导致的急性肾衰竭：两例报告

Acute renal failure due to indinavir crystalluria and nephrolithiasis: report of two cases.

作者信息

Berns J S, Cohen R M, Silverman M, Turner J

机构信息

Department of Medicine, Allegheny University Hospitals, Graduate, Philadelphia, PA 19146, USA.

出版信息

Am J Kidney Dis. 1997 Oct;30(4):558-60. doi: 10.1016/s0272-6386(97)90316-4.

DOI:10.1016/s0272-6386(97)90316-4

PMID:9328372

Abstract

Two patients with oliguric acute renal failure (ARF) attributed to crystalluria and nephrolithiasis with obstructive uropathy caused by the human immunodeficiency virus protease inhibitor indinavir are described. In both patients, ARF resolved with administration of intravenous fluids. One patient required urologic intervention to relieve bilateral ureteral obstruction.

摘要

描述了两名因结晶尿、肾结石及由人类免疫缺陷病毒蛋白酶抑制剂茚地那韦引起的梗阻性尿路病导致少尿性急性肾衰竭（ARF）的患者。两名患者经静脉补液后急性肾衰竭均得到缓解。一名患者需要进行泌尿外科干预以解除双侧输尿管梗阻。