Dinovo E C, Gottschalk L A, Nandi B R, Geddes P G
J Pharm Sci. 1976 May;65(5):667-9. doi: 10.1002/jps.2600650509.
A GLC method for measuring thioridazine, mesoridazine, their metabolites, and possibly other phenothiazines was developed. By using this method, seven different phenothiazine derivatives, thioridazine, and six known thioridazine metabolites were extracted and separated. This method was tested by assaying plasma samples from 30 hospitalized psychiatric patients receiving thioridazine or mesoridazine.
开发了一种用于测定硫利达嗪、美索达嗪、它们的代谢物以及可能的其他吩噻嗪类药物的气相色谱法。通过使用该方法，提取并分离了七种不同的吩噻嗪衍生物、硫利达嗪和六种已知的硫利达嗪代谢物。通过对30名接受硫利达嗪或美索达嗪治疗的住院精神病患者的血浆样本进行分析，对该方法进行了测试。
