Weiner B K, Fraser R D
Royal Adelaide Hospital, Australia.
J Bone Joint Surg Br. 1997 Sep;79(5):804-7. doi: 10.1302/0301-620x.79b5.7636.
Between 1986 and 1995, we treated with foraminal injection of local anaesthetic and steroids 30 patients with severe lumbar radiculopathy secondary to foraminal and extraforaminal disc herniation which had not resolved with rest and non-steroidal anti-inflammatory agents. They were assessed prospectively using standardised forms as well as the Low Back Outcome Score, and were reviewed at an average of 3.4 years (1 to 10) after injection by an independent observer (BKW). Relief of symptoms was obtained in 27 immediately after injection. Three subsequently relapsed, requiring operation, and two were lost to long-term follow-up. Thus 22 of the 28 patients available for long-term follow-up had considerable and sustained relief from their symptoms. Before the onset of symptoms 17 were in employment and, after injection, 13 resumed work, all but two in the same job. The average score before injection was 25 out of a possible 75 points. At follow-up, the overall average score was 54, and in those who had obtained relief of symptoms it had improved to a mean of 61. Based on these findings we recommend foraminal injection of local anaesthetic and steroids as the primary treatment for patients with severe radiculopathy secondary to foraminal or extraforaminal herniation of a lumbar disc.
1986年至1995年间,我们对30例因椎间孔和椎间孔外椎间盘突出继发严重腰椎神经根病且经休息和非甾体抗炎药治疗未缓解的患者进行了椎间孔注射局部麻醉剂和类固醇治疗。使用标准化表格以及腰椎结局评分对他们进行前瞻性评估,并由独立观察者(BKW)在注射后平均3.4年(1至10年)进行复查。注射后立即有27例症状得到缓解。其中3例随后复发,需要手术治疗,2例失访。因此,在可供长期随访的28例患者中,有22例症状得到了显著且持续的缓解。症状出现前有17人就业,注射后有13人恢复工作,除两人外均从事原工作。注射前平均得分为75分中的25分。随访时,总体平均得分为54分,症状得到缓解的患者平均得分提高到61分。基于这些发现,我们建议对因腰椎间盘椎间孔或椎间孔外突出继发严重神经根病的患者,将椎间孔注射局部麻醉剂和类固醇作为主要治疗方法。