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眼眶囊尾蚴病

Orbital cysticercosis.

作者信息

Sekhar G C, Lemke B N

机构信息

Oculoplastic and Orbital Disease Service, L. V. Prasad Eye Institute, Hyderabad, India.

出版信息

Ophthalmology. 1997 Oct;104(10):1599-604. doi: 10.1016/s0161-6420(97)30090-6.

Abstract

BACKGROUND

Human cysticercosis is secondary to an infestation by cysticercus cellulosae, the larval form of Taenia solium. Cysticercosis is endemic to regions with poor sanitation. The purpose of this report is to present a large series of patients with orbital cysticercosis and to discuss the current treatment.

METHODS

A retrospective chart analysis of all patients with orbital cysticercosis from an urban practice in southern India was performed. The clinical features, the results of investigations, the therapies instituted, and the outcomes realized were recorded.

RESULTS

Twenty patients diagnosed with orbital cysticercosis were identified (11 female and 9 male). Their ages ranged from 5 to 25 years with a mean age of 12.5 years. Nine patients manifested subconjunctival cysts. Eight were excised and 5 of these were densely adherent to the adjacent extraocular muscle (EOM). The remaining 11 patients had a cyst in a single EOM. The EOM cysts had proptosis, restricted motility, recurrent inflammation, and blepharoptosis. Two of the EOM cysts were excised surgically and four extruded spontaneously. Six patients with EOM cysts were treated medically: they all received oral corticosteroids and, additionally, five were given oral albendazole and one was given oral praziquantel.

CONCLUSIONS

Excisional biopsy is recommended for subconjunctival cysticercosis. Idiopathic cystic myositis can present like EOM cysticercosis, but is differentiated by resolution with corticosteroid treatment. Medical therapy in orbital cysticercosis with oral albendazole and corticosteroids can arrest recurrent inflammation and improve ocular motility.

摘要

背景

人体囊尾蚴病继发于猪带绦虫幼虫囊尾蚴的感染。囊尾蚴病在卫生条件差的地区为地方病。本报告的目的是呈现一大系列眼眶囊尾蚴病患者并讨论当前的治疗方法。

方法

对印度南部一家城市医疗机构中所有眼眶囊尾蚴病患者进行回顾性病历分析。记录临床特征、检查结果、所采用的治疗方法及取得的疗效。

结果

确诊为眼眶囊尾蚴病的患者有20例(女性11例,男性9例)。年龄范围为5至25岁,平均年龄12.5岁。9例患者表现为结膜下囊肿。其中8例被切除,5例与相邻眼外肌紧密粘连。其余11例患者在单一眼外肌中有囊肿。眼外肌囊肿表现为眼球突出、活动受限、反复炎症和上睑下垂。2例眼外肌囊肿通过手术切除,4例自行排出。6例眼外肌囊肿患者接受药物治疗:均口服皮质类固醇,另外5例加服口服阿苯达唑,1例加服口服吡喹酮。

结论

对于结膜下囊尾蚴病,建议进行切除活检。特发性囊肿性肌炎可表现得像眼外肌囊尾蚴病,但通过皮质类固醇治疗后病情缓解可加以鉴别。眼眶囊尾蚴病采用口服阿苯达唑和皮质类固醇进行药物治疗可抑制反复炎症并改善眼球运动。

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