Ycas M
J Mol Evol. 1976 Apr 9;7(3):215-44. doi: 10.1007/BF01731490.
Using, in part, comparisons between reconstructed ancestral sequences, homologies are suggested between certain proteins. Genetically related groups seem to be: 1. pancreatic and bacterial nucleases, 2. lysozymes and subtilisins, 3. c type cytochromes, ferredoxins and rubredoxins, 4. b type cytochromes, myoglobins and hemoglobins, catalase, and glutamic dehydrogenase. These homologies suggest that a given ancestral sequence can evolve into quite different tertiary structures.
部分通过比较重建的祖先序列,发现某些蛋白质之间存在同源性。遗传相关的组似乎有:1. 胰腺核酸酶和细菌核酸酶;2. 溶菌酶和枯草杆菌蛋白酶;3. c型细胞色素、铁氧化还原蛋白和红素氧还蛋白;4. b型细胞色素、肌红蛋白和血红蛋白、过氧化氢酶和谷氨酸脱氢酶。这些同源性表明,一个给定的祖先序列可以进化成截然不同的三级结构。