Chico M, Sandoval C, Guevara A, Calvopiña M, Cooper P J, Reed S G, Guderian R H
Departamento de Investigaciones Clínicas, Hospital Vozandes, HCJB, Quito, Ecuador.
Mem Inst Oswaldo Cruz. 1997 May-Jun;92(3):317-20. doi: 10.1590/s0074-02761997000300002.
Two well-defined synthetic peptides TcD and PEP2 were used in a sero-epidemiological study for the detection of Trypanosoma cruzi infections in an indigenous group in the Amazon region of Ecuador. Of the 18 communities studied along the Rio Napo, province of Napo, 15 (83.3%) were found to be positive for T. cruzi infection. Of the 1,011 individuals examined 61 (6.03%) resulted positive. A prevalence of infection of 4.8% was found in children aged 1-5 years. The prevalence of infection increased with age, with adults 50 years or older showing a maximum prevalence of 18.8%. Autochthonous transmission of T. cruzi is present among this isolated indigenous population.
两种明确的合成肽TcD和PEP2被用于一项血清流行病学研究,以检测厄瓜多尔亚马逊地区一个原住民群体中的克氏锥虫感染情况。在纳波省纳波河沿岸研究的18个社区中,有15个(83.3%)被发现克氏锥虫感染呈阳性。在接受检查的1011人中,有61人(6.03%)结果呈阳性。在1至5岁的儿童中发现感染率为4.8%。感染率随年龄增长而上升,50岁及以上的成年人感染率最高,为18.8%。在这个与世隔绝的原住民群体中存在克氏锥虫的本地传播。