Amunárriz Manuel, Quito Segundo, Tandazo Víctor, López Mayra
Hospital Franklin Tello, Nuevo Rocafuerte, Orellana, Ecuador.
Rev Panam Salud Publica. 2010 Jul;28(1):25-9. doi: 10.1590/s1020-49892010000700004.
Determine the current seroprevalence of Chagas disease in the population of Aguarico canton, and compare the findings with data from other epidemiological studies.
From September 2008 to October 2009, 2 033 serum samples were collected from 36.6% of the total population in Aguarico canton. The Chagatest recombinant ELISA v.3.0 was used to determine positivity to Chagas disease. Cases that tested positive were confirmed by indirect hemagglutination and ELISA.
Of the 2 033 serum samples obtained, 73 tested positive for Chagas disease (3.6%). Seroprevalence in communities with positive cases ranged from 1.4% to 13.3%, with 60.3% of the positive cases found in females. These findings are similar to the 1990 comparison studies.
The data obtained confirm the existence of an indigenous focus of Chagas disease in the Ecuadorian Amazon, with a percentage higher that the average for the Amazon region. No acute clinical cases or chronic pathologies were detected. Implementation of a culturally appropriate Chagas control program for the region is urgently needed.
确定阿瓜里科县人群中恰加斯病的当前血清阳性率，并将研究结果与其他流行病学研究的数据进行比较。
2008年9月至2009年10月，从阿瓜里科县36.6%的总人口中采集了2033份血清样本。使用Chagatest重组酶联免疫吸附测定法v.3.0来确定恰加斯病的阳性情况。检测呈阳性的病例通过间接血凝试验和酶联免疫吸附测定法进行确认。
在获得的2033份血清样本中，73份恰加斯病检测呈阳性（3.6%）。有阳性病例的社区血清阳性率在1.4%至13.3%之间，60.3%的阳性病例为女性。这些结果与1990年的比较研究相似。
获得的数据证实了厄瓜多尔亚马逊地区存在恰加斯病的本土疫源地，其百分比高于亚马逊地区的平均水平。未检测到急性临床病例或慢性病理情况。迫切需要为该地区实施适合当地文化的恰加斯病控制项目。
