Guevara Angel G, Atherton Richard D, Wauters Michael A, Vicuña Yosselin, Nelson Marcos, Prado Jose, Kato Hirotomo, Calvopiña Manuel H, Hashiguchi Yoshihisa
Laboratorio de Parasitologia Molecular y Medicina Tropical, Centro de Biomedicina, Facultad de Medicina, Universidad Central del Ecuador, Quito, Ecuador.
Trop Med Health. 2013 Mar;41(1):21-5. doi: 10.2149/tmh.2012-31. Epub 2013 Feb 14.
To determine the extent of Trypanosoma cruzi infection and/or transmission in the southern Amazon region of Ecuador, three indigenous communities in the provinces of Pastaza and Morona Santiago were serosurveyed. Chagatest(TM), Immunocomb(®)II and immunofluorescent (IF) assays were used. Among the 385 inhabitants examined, nine (2.34%) were seropositive for T. cruzi infection. Of the nine positive sera, four (44.4%) fall in the 10-19, one each in the 20-29, 30-39 and 40-49, and two in the 50-59 age groups. These results suggested the possible existence of an autochthonous active T. cruzi transmission in the region and provide the first serological evidence for T. cruzi infection in the southern province of Morona Santiago bordering Peru. Further studies are needed in these Amazonian provinces to ascertain the spread of T. cruzi infection in the area.
为确定克氏锥虫在厄瓜多尔亚马逊地区南部的感染和/或传播程度，对帕斯塔萨省和莫罗纳 - 圣地亚哥省的三个土著社区进行了血清学调查。使用了Chagatest™、Immunocomb®II和免疫荧光（IF）检测方法。在接受检查的385名居民中，有9人（2.34%）克氏锥虫感染血清学呈阳性。在这9份阳性血清中，4份（44.4%）属于10 - 19岁年龄组，20 - 29岁、30 - 39岁和40 - 49岁年龄组各有1份，50 - 59岁年龄组有2份。这些结果表明该地区可能存在克氏锥虫的本地主动传播，并为与秘鲁接壤的南部莫罗纳 - 圣地亚哥省的克氏锥虫感染提供了首个血清学证据。需要在这些亚马逊省份开展进一步研究，以确定该地区克氏锥虫感染的传播情况。
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