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[伴有假性缺血和高血压临床表现的甲状腺功能减退症:生理病理学及诊断方面的考量]

[Hypothyroidism with pseudo-ischemic and hypertensive clinical presentation: physiopathological and diagnostic considerations].

作者信息

La Brocca A

机构信息

Divisione di Medicina Interna, Ospedale Civile di Giaveno (TO), Azienda Regionale U.S.L. 5 di Torino.

出版信息

Ann Ital Med Int. 1997 Apr-Jun;12(2):94-7.

PMID:9333319
Abstract

Serious primary hypothyroidism, disclosed fortuitously through routine thyroid function test derangements, was found in a 40-year-old woman admitted to the hospital with a tentative diagnosis of ischemic heart disease. The clinical picture and electrocardiographic alterations of pseudo-ischemic heart disease associated with hypertension, particularly diastolic, may be the only significant manifestations of hypothyroidism. Substitutive hormone replacement therapy enables a good prognosis for children and young adults. A diagnosis of hypothyroidism should be considered during the initial evaluation of pseudo-ischemic, hypertensive and hypercholesterolemic patients, even when no other signs or clinical symptoms of hormonal deficiency are evident. Particular attention should be paid to female patients, as they are much more frequently affected by thyroid pathologies.

摘要

一名40岁女性因初步诊断为缺血性心脏病入院,通过常规甲状腺功能检查紊乱偶然发现患有严重原发性甲状腺功能减退症。与高血压(尤其是舒张期高血压)相关的假性缺血性心脏病的临床表现和心电图改变可能是甲状腺功能减退症的唯一显著表现。替代激素替代疗法对儿童和年轻人预后良好。在对假性缺血性、高血压和高胆固醇血症患者进行初步评估时,即使没有明显的激素缺乏其他体征或临床症状,也应考虑甲状腺功能减退症的诊断。应特别关注女性患者,因为她们更易患甲状腺疾病。

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