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[1984年至1993年捷克共和国心血管疾病死亡率的下降及其可能原因]

[Decrease in cardiovascular disease mortality in the Czech Republic from 1984 to 1993 and its possible causes].

作者信息

Skodová Z, Písa Z, Poledne R, Berka L, Cícha Z, Emrová R, Hoke M, Pikhartová J, Vojtísek P, Grafnetter D, Wiesner E, Hrdlicková K, Havlíková A, Bobák M, Vorlícek J, Paclt M, Lánská V

机构信息

Pracovistĕ preventivní kardiologie IKEM, Praha.

出版信息

Cas Lek Cesk. 1997 Jun 12;136(12):373-9.

PMID:9333509
Abstract

BACKGROUND

The objective of the investigation was to evaluate the ten-year development of the cardiovascular mortality rate in two population groups in the age bracket from 25 to 64 years, i.e. in subjects living in six districts which participated in the international WHO project MONICA and in the population of the whole Czech Republic.

METHODS AND RESULTS

Data on the mortality rate in 1984-1993 for the age group from 25-64 years were provided by the Institute of Health Information and Statistics, information on the prevalence of risk factors was obtained in three cross-sectional studies implemented in six districts as part of the MONICA project in 1985, 1988 and 1992. In the mortality rate per 100,000 population in the six districts the following changes were revealed (in parentheses the values for 1984 and 1993 are given): men - a statistically significant declining trend in the from all caused mortality (849.3-742.5; p < 0.001) and cardiovascular mortality (367.2-280.4; p < 0.001) and cerebrovascular mortality (69.7-44.8; p < 0.001). In the mortality from ischaemic heart disease (215.7-170.6; ns) a declining trend was not recorded. In women aged 25-64 years in the six districts there was a statistically significant decline of the mortality from all caused (359.5-322.1; p < 0.001), the cardiovascular mortality (115.6-100.6; p < 0.001) and cerebrovascular mortality (31.1-23.6; p < 0.001). The mortality from ischaemic heart disease did not change (49.2-48.8; ns). In the population of the Czech Republic in men the following were detected: a drop of the from all caused mortality (907.1-784.8; P < 0.001), the cardiovascular mortality (383.5-308.4; p < 0.001) and cerebrovascular mortality (76.5-55.3; p < 0.001). Also in women of the Czech Republic a decline of the mortality from all caused was recorded (390.1-328.5; p < 0.001), the cardiovascular mortality (135.3-103.8; p < 0.001), ischaemic heart disease (58.0-48.6; p < 0.001) and cerebrovascular mortality (43.5-27.4; p < 0.001). In 1990 an increased cardiovascular mortality was recorded in men different from the trend during 1984-1993, statistically significant in the Czech Republic (p < 0.05) and in the six districts (p < 0.05). The reasons of this trend are not clear. The role of health services in the mortality drop is not clear, although available data indicate their improvement. Favourable changes were found in risk factors: during the period from 1985-1992 the prevalence of hypercholesterolaemia declined significantly in men and women, the prevalence of hypertension in women and the prevalence of smoking in men declined in the six districts. From nationwide data ensues that after 1989 significant changes occurred in the diet of the Czech population. The meat consumption declined by 1993 by 13%, the milk and dairy product consumption by 26.8% the butter consumption by 43.6% the consumption of vegetable fats increased by 16%, of vegetables by 8%, tropical fruit by 43.2%. These changes probably had an impact on the cholesterol level and BMI of the Czech population.

CONCLUSIONS

In the declining cardiovascular mortality trend during 1984-1993 the following may have participated: improved medical care, dietary changes, improvement of the risk profile and other, in particular socioeconomic factors. With regard to the close temporal association of the investigated changes it may be assumed that this development is at least partly associated with changes of the political and economic position in the Czech Republic after 1989.

摘要

背景

本研究旨在评估年龄在25至64岁的两个人口群体中心血管死亡率的十年发展情况,即参与世界卫生组织国际项目MONICA的六个地区的居民以及整个捷克共和国的人口。

方法与结果

1984 - 1993年25 - 64岁年龄组的死亡率数据由卫生信息与统计研究所提供,危险因素患病率信息来自于1985年、1988年和1992年在六个地区开展的三项横断面研究,这些研究是MONICA项目的一部分。六个地区每10万人口的死亡率出现了以下变化(括号内为1984年和1993年的值):男性——全因死亡率(849.3 - 742.5;p < 0.001)、心血管死亡率(367.2 - 280.4;p < 0.001)和脑血管死亡率(69.7 - 44.8;p < 0.001)均呈现出具有统计学意义的下降趋势。缺血性心脏病死亡率(215.7 - 170.6;无统计学意义)未呈现下降趋势。在六个地区25 - 64岁的女性中,全因死亡率(359.5 - 322.1;p < 0.001)、心血管死亡率(115.6 - 100.6;p < 0.001)和脑血管死亡率(31.1 - 23.6;p < 0.001)均有统计学意义的下降。缺血性心脏病死亡率未发生变化(49.2 - 48.8;无统计学意义)。在捷克共和国的男性人口中,发现全因死亡率(907.1 - 7***.8;P < 0.001)、心血管死亡率(383.5 - 308.4;p < 0.001)和脑血管死亡率(76.5 - 55.3;p < 0.001)均有所下降。在捷克共和国的女性中也记录到全因死亡率下降(390.1 - 328.5;p < 0.001)、心血管死亡率(135.3 - 103.8;p < 0.001)、缺血性心脏病死亡率(58.0 - 48.6;p < 0.001)和脑血管死亡率(43.5 - 27.4;p < 0.001)。1990年,男性心血管死亡率出现上升,与1984 - 1993年的趋势不同,在捷克共和国(p < 0.05)和六个地区(p < 0.05)具有统计学意义。这种趋势的原因尚不清楚。尽管现有数据表明卫生服务有所改善,但其在死亡率下降中的作用尚不清楚。在危险因素方面发现了有利变化:1985 - 1992年期间,男性和女性的高胆固醇血症患病率显著下降,六个地区女性的高血压患病率和男性的吸烟率下降。从全国数据可知,1989年后捷克人口的饮食发生了显著变化。到1993年,肉类消费量下降了13%,牛奶和奶制品消费量下降了26.8%,黄油消费量下降了43.6%;植物脂肪消费量增加了16%,蔬菜消费量增加了8%,热带水果消费量增加了43.2%。这些变化可能对捷克人口的胆固醇水平和体重指数产生了影响。

结论

1984 - 1993年心血管死亡率下降趋势可能与以下因素有关:医疗保健改善、饮食变化、危险因素状况改善以及其他因素,特别是社会经济因素。考虑到所研究变化的紧密时间关联,可以假设这种发展至少部分与1989年后捷克共和国政治和经济状况的变化有关。

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