[捷克共和国代表性人群样本中总胆固醇和高密度脂蛋白胆固醇的纵向趋势]

[Longitudinal trends of total and HDL cholesterol in a representative population sample in the Czech Republic].

作者信息

Cífková R, Skodová Z, Lánská V, Poledne R, Adámková V, Novozámská E, Jozífová M, Petrzílková Z, Hauserová G, Dusková A, Hejl Z, Stávek P, Skibová J

机构信息

Pracovistĕ preventivní kardiologie IKEM, Praha.

出版信息

Vnitr Lek. 2000 Sep;46(9):501-5.

PMID:11344640

Abstract

Cardiovascular diseases are the main cause of death in the Czech Republic. Since 1984 there is a decline of the total and cardiovascular mortality in the CR which is due to a decline of the mortality from IHD and cerebrovascular disease. Within the framework of the MONICA project in 1985, 1988 and 1992 in six districts of the CR screening examinations of cardiovascular disease risk factors were made. For examination always 1% of the population aged 25-64 years (random sampling) was invited. In 1997 and 1998 a similar cross-sectional surmy was made in nine districts of the CR. A total of 3,209 subjects were examined. In 1985-1997/98 in the representative population samples of six districts of the CR there was a significant decline of total cholesterol (men from 6.21 +/- 1.29 to 5.65 +/- 1.15 mmol/l, p < 0.001, women from 6.18 +/- 1.26 to 5.53 +/- 1.21 mmol/l, p < 0.001 and the total cholesterol/HDL ratio (men from 4.94 +/- 1.83 mmol/l to 4.66 +/- 1.46, p < 0.001, women from 4.14 +/- 1.32 to 3.89 +/- 1.30 mmol/l p < 0.001).

摘要

心血管疾病是捷克共和国的主要死因。自1984年以来，捷克共和国的总死亡率和心血管疾病死亡率呈下降趋势，这是由于缺血性心脏病和脑血管疾病死亡率的下降。在1985年、1988年和1992年的莫妮卡项目框架内，对捷克共和国六个地区的心血管疾病危险因素进行了筛查检查。每次检查都邀请25至64岁人群的1%（随机抽样）。1997年和1998年，在捷克共和国的九个地区进行了类似的横断面调查。总共检查了3209名受试者。1985年至1997/98年，在捷克共和国六个地区具有代表性的人群样本中，总胆固醇显著下降（男性从6.21±1.29降至5.65±1.15 mmol/l，p<0.001；女性从6.18±1.26降至5.53±1.21 mmol/l，p<0.0:01）以及总胆固醇/高密度脂蛋白比值（男性从4.94±1.83 mmol/l降至4.66±1.46，p<0.001；女性从4.14±1.32降至3.89±1.30 mmol/l，p<0.001）。