Wyss E, Candinas R
Abteilung Kardiologie, Universitätsspital, Zürich.
Ther Umsch. 1997 Mar;54(3):144-50.
Bradyarrhythmias are the cause of syncope in 3 to 10% of cases. Marked bradycardia or asystole can be due to impaired function of the sinus node (sick sinus syndrome), high degree AV block or neurocardiogenic disorders (carotid sinus syndrome, vasovagal syncope). A precise history, ECG and 24-h. Holter recordings are the most helpful tools in diagnosis of bradyarrhythmia-induced syncope. An association between symptoms and documented ECG is essential for proper diagnosis. Sometimes an event-recorder may be helpful for this purpose. If a patient has normal physical examination, ECG, Holter, stress test, tilt-table test and echocardiography, no further electrophysiological investigation is needed. If the noninvasive tests show pathologic results that do not clearly explain the cause of syncope (sinus bradycardia, first-degree AV block, fascicular block, structural heart disease), then electrophysiological studies are recommended, which will also rule out ventricular tachyarrythmias in the differential diagnosis. If all diagnostic tests in a patient with syncope are normal, the prognosis is fairly good despite 30% recurrence rate. Treatment for symptomatic bradyarrhythmias is implantation of a pacemaker. The selection of an appropriate pacemaker system is very important. Dual-chamber systems (DDD) provide physiological stimulation by maintaining AV synchrony; thus, they should be preferred whenever possible.
缓慢性心律失常是3%至10%的晕厥病例的病因。显著的心动过缓或心搏停止可能是由于窦房结功能受损(病态窦房结综合征)、高度房室传导阻滞或神经心源性疾病(颈动脉窦综合征、血管迷走性晕厥)。详细的病史、心电图和24小时动态心电图记录是诊断缓慢性心律失常所致晕厥最有用的工具。症状与记录的心电图之间的关联对于正确诊断至关重要。有时事件记录仪对此可能会有帮助。如果患者体格检查、心电图、动态心电图、负荷试验、倾斜试验和超声心动图均正常,则无需进一步进行电生理检查。如果无创检查显示病理性结果但不能明确解释晕厥原因(窦性心动过缓、一度房室传导阻滞、束支阻滞、结构性心脏病),则建议进行电生理研究,这也将在鉴别诊断中排除室性心律失常。如果晕厥患者的所有诊断检查均正常,尽管复发率为30%,预后仍相当良好。有症状的缓慢性心律失常的治疗方法是植入起搏器。选择合适的起搏器系统非常重要。双腔系统(DDD)通过维持房室同步提供生理性刺激;因此,应尽可能首选双腔系统。