Kühlkamp V, Seipel L
Abteilung III, Eberhard-Karls-Universität Tübingen.
Herz. 1993 Jun;18(3):182-6.
Bradyarrhythmias, depending on the patient population, are the cause of syncope in 3 to 10%. Marked bradycardia or asystole can be due to impaired function of the sinus node (sinus node syndrome) or high-grade AV-conduction block as well as carotid sinus syndrome and pathologic vasodepressor reactions. In particular, in the presence of high-grade AV-block, the diagnosis of bradyarrhythmia-induced syncope can frequently be established on the basis of a standard ECG. One of the most common causes of syncope is functional impairment of the sinus node, in particular, an inadequate permanent sinus bradycardia, sinus node arrest or SA-block and paroxysmal atrial tachycardia alternating with atrial bradycardia. The method of choice for detecting suspected paroxysmal arrthythmias is ambulatory ECG monitoring but interpretation may be encumbered by the absence of concomitant symptoms during the registration. Frequently, the use of non-invasive methods alone, such as detailed history, ambulatory ECG and ECG exercise testing, will not render confirmatory findings to document the cause of syncope, that is, > 3 s pause in sinus rhythm or high-grade AV-block. In this situation, the question arises which patients should undergo electrophysiologic examination. Several studies have shown that in patients with a pathologic resting ECG (first degree AV-block, bundle branch block, inadequate sinus bradycardia) and cardiac disease, electrophysiologic studies will document a cause of syncope in more than 30%.(ABSTRACT TRUNCATED AT 250 WORDS)
根据患者群体的不同,缓慢性心律失常导致晕厥的比例为3%至10%。显著的心动过缓或心搏停止可能是由于窦房结功能受损(窦房结综合征)、高度房室传导阻滞、颈动脉窦综合征以及病理性血管减压反应。特别是在存在高度房室传导阻滞的情况下,常常可以根据标准心电图确诊缓慢性心律失常所致的晕厥。晕厥最常见的原因之一是窦房结功能障碍,尤其是永久性窦性心动过缓、窦房结停搏或窦房阻滞不充分,以及阵发性房性心动过速与房性心动过缓交替出现。检测疑似阵发性心律失常的首选方法是动态心电图监测,但记录过程中缺乏伴随症状可能会影响解读。通常,仅使用非侵入性方法,如详细病史、动态心电图和心电图运动试验,无法得出确诊结果来证明晕厥的原因,即窦性心律停搏>3秒或高度房室传导阻滞。在这种情况下,就会出现哪些患者应接受电生理检查的问题。多项研究表明,对于静息心电图异常(一度房室传导阻滞、束支传导阻滞、窦性心动过缓不充分)且患有心脏病的患者,电生理检查可发现超过30%的晕厥病因。(摘要截选至250词)