Marín P
Unidad de Cuidados Intensivos, Servicio de Medicina, Hospital Regional de Talca.
Rev Med Chil. 1996 Dec;124(12):1492-5.
Hydrochlorotiazide may cause pulmonary dema. We report two female patients aged 58 and 69 years old, who after the ingestion of this diuretic, were admitted to an intensive care unit with fever, digestive symptoms, severe dyspnea, hypotension and a hemodynamic pattern resembling hypovolemia. Both had a good response to volume repletion and vasoactive drugs. Despite the severity of the clinical picture, they had a full and fast recovery. This type of reaction to hydrochlorotiazide is probably idiosyncratic and must be considered in the differential diagnosis of pulmonary edema.
氢氯噻嗪可能导致肺水肿。我们报告了两名分别为58岁和69岁的女性患者，她们在服用这种利尿剂后，因发热、消化症状、严重呼吸困难、低血压以及类似低血容量的血流动力学模式而被收入重症监护病房。两人对液体补充和血管活性药物均有良好反应。尽管临床表现严重，但她们都实现了完全且快速的康复。这种对氢氯噻嗪的反应可能是特异质的，在肺水肿的鉴别诊断中必须予以考虑。
