Kimura S
Acta Derm Venereol. 1979;59(5):415-9.
Mast cells in three cases of solitary glomus tumor were examined by light and electron microscopy. As seen by light microscopy, a number of round, oval or elongated mast cells were distributed throughout the stromal connective tissue and showed slight or moderate metachromasia when stained with toluidine blue (pH 4.1). Electron microscopy revealed various types and degrees of degranulation of mast cell granules, and also disclosed a close correlation between mast cells and non-myelinated nerve fibers. These findings suggest that mast cells may play an algogenic role in solitary glomus tumors, probably mediated by the contents, mainly histamine, concentrated in their granules.
对3例孤立性血管球瘤中的肥大细胞进行了光镜和电镜检查。光镜下可见，许多圆形、椭圆形或细长形的肥大细胞分布于整个间质结缔组织中，用甲苯胺蓝（pH 4.1）染色时显示轻度或中度异染性。电镜检查发现肥大细胞颗粒有不同类型和程度的脱颗粒现象，还揭示了肥大细胞与无髓神经纤维之间存在密切相关性。这些发现提示肥大细胞可能在孤立性血管球瘤中发挥致痛作用，可能是由其颗粒中浓缩的主要成分组胺介导的。
