Ratón J A, Pocheville I, Vicente J M, González R, Bilbao I, Gutierrez C, Díaz-Pérez J L
Department of Dermatology, Cruces Hospital, Bilbao, Spain.
Pediatr Dermatol. 1997 Sep-Oct;14(5):365-8. doi: 10.1111/j.1525-1470.1997.tb00983.x.
A boy born to a mother with unknown HIV infection was immunized with BCG in his first month of life. Seven months later axillary adenopathy developed. At the age of 10 months, 2 months after HIV infection had been diagnosed, papular skin lesions appeared all over his body. Mycobacterium bovis, BCG strain, was cultured from a lymph node and blood. Ziehl-Neelsen stain of a skin biopsy specimen showed histiocytes loaded with numerous acid-fast bacilli. The patient died 10 days later, before the infection was confirmed. This is the first reported case of disseminated BCG infection in an HIV-infected child presenting with cutaneous lesions.
一名母亲HIV感染状况不明的男婴在出生后第一个月接种了卡介苗。七个月后出现腋窝淋巴结病。10个月大时，在确诊感染HIV两个月后，他全身出现丘疹性皮肤病变。从淋巴结和血液中培养出牛分枝杆菌卡介苗菌株。皮肤活检标本的萋-尼染色显示组织细胞内充满大量抗酸杆菌。患者在感染确诊前10天死亡。这是首例有皮肤病变表现的HIV感染儿童播散性卡介苗感染的报道病例。
