Neely J G, Britton B H, Greenberg S D
Laryngoscope. 1976 Jul;86(7):984-91. doi: 10.1288/00005537-197607000-00012.
The microscopic characteristics of a 0.9 cm vestibular schwannoma en bloc resected with its nerve of origin which occurred in a 54-year-old white woman presenting with a two-year history of a unilateral progressive sensori-neural hearing loss is described. The tumor originated in the inferior vestibular portion of the vestibular division of the VIIIth cranial nerve just medial to the internal auditory canal meatus at approximately the level of the glial-non-glial junction. The tumor demonstrated two distinctly different, yet simultaneous, modes of involvement with its nerve of origin: 1. inseparable cellular continuity; and 2. peripheral compression of the remainder of the nerve within the tumor capsule. Despite only slight microscopic continuity of the nerve histologically, electronystagmography showed no unilateral weakness on bithermal caloric testing, and pure tone and speech audiometry was only moderately depressed.
描述了一名54岁白人女性的0.9厘米前庭神经鞘瘤与其起源神经整块切除的微观特征，该患者有两年单侧进行性感音神经性听力损失病史。肿瘤起源于第八颅神经前庭分支的下前庭部分，恰在内耳道开口内侧，大约在神经胶质 - 非神经胶质交界处水平。肿瘤与其起源神经表现出两种截然不同但同时存在的累及方式：1. 不可分离的细胞连续性；2. 肿瘤包膜内对神经其余部分的外周压迫。尽管在组织学上神经仅有轻微的微观连续性，但眼震电图显示冷热试验时无单侧无力，纯音及言语听力测定仅中度降低。
