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[通过米德布鲁克-杜博斯、博伊登和库姆斯血凝试验对人体中完全抗体和不完全抗体的比较]

[A comparison of complete and incomplete antibodies by Middlebrook-Dubos, Boyden and Coombs hemagglutination tests in man].

作者信息

Mercangös F

出版信息

Mikrobiyol Bul. 1976 Feb;10(2):189-202.

PMID:933898
Abstract

The antibodies in the sera of 160 tuberculous persons and in a control group of 100 healthy persons were investigated by Middlebrook-Dubos (M-D), Boyden hemagglutination and modified M-D antiglobulin methods. By the M-D method 88% of the sera from 135 persons with lung tuberculosis, and 57.1% sera from 21 persons with other organ tuberculosis gave positive results. In the control group of 100 persons 11% were positive, while all of PPD negative persons remained negative. By Boyden method 90% of 135 lung tuberculosis, 57.1% of 21 with other organ tuberculosis and 4% of the control group gave positive results. In 91.2% of 80 persons with lung tuberculosis, tested with modified M-D antiglobulin method, found incomplete antibodies. The difference in control groups (11%, 4%), and in persons with active tuberculosis (88%, 90%) indicates that the serological tests are just as significant as other diagnostic methods.

摘要

采用Middlebrook - Dubos(M - D)法、博伊登血细胞凝集法和改良M - D抗球蛋白法,对160例结核病患者血清及100例健康对照者血清中的抗体进行了检测。采用M - D法,135例肺结核患者血清中88%呈阳性,21例其他器官结核患者血清中57.1%呈阳性。在100例对照者中,11%呈阳性,而所有PPD阴性者均为阴性。采用博伊登法,135例肺结核患者中90%呈阳性,21例其他器官结核患者中57.1%呈阳性,对照组中4%呈阳性。用改良M - D抗球蛋白法检测的80例肺结核患者中,91.2%发现不完全抗体。对照组(11%、4%)与活动性结核患者(88%、90%)之间的差异表明,血清学检测与其他诊断方法同样重要。

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