Gendrel D
Service de pédiatrie générale Hôpital Saint-Vincent-de-Paul, Paris.
Rev Prat. 1997 Sep 1;47(13):1434-7.
Measles is an acute disease characterized by fever, cough, conjunctivitis, erythematous maculopapular rash and pathognomonic enanthem. Vaccination had resulted in decrease of complications and mortality. But vaccination coverage in France is low, about 80%: the virus is always circulating and outbreaks in teenagers are possible. The recommendation of a booster dose at age eleven will contribute to reduce the incidence of the disease. Rubella is asymptomatic in 30 to 50% of infected children. There is a risk of transmission to pregnant women with negative serology. Reduction of virus circulation and immunization of young girls will result in decrease of the congenital rubella syndrome (65 cases/year in France). A vaccine booster dose at eleven in all children, combined with measles immunization, is necessary.
麻疹是一种急性疾病,其特征为发热、咳嗽、结膜炎、红色斑丘疹和特征性黏膜疹。疫苗接种已使并发症和死亡率有所降低。但法国的疫苗接种覆盖率较低,约为80%:病毒一直在传播,青少年中有可能暴发疫情。建议在11岁时接种加强针将有助于降低该疾病的发病率。30%至50%的受感染儿童感染风疹后无症状。血清学检查呈阴性的孕妇有被传染的风险。减少病毒传播以及对年轻女孩进行免疫接种将降低先天性风疹综合征的发病率(法国每年有65例)。对所有儿童在11岁时接种加强针,并与麻疹免疫接种相结合是必要的。