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萎缩性多软骨炎主动脉瓣关闭不全的解剖临床研究。附1例报告

[Anatomoclinical study of aortic insufficiency in atrophic polychondritis. Apropos of a case].

作者信息

Thuaire C, Benamer H, Brochet E, Aubry P, Hayem G, Vissuzaine C, Chatel D, Assayag P

机构信息

Service de cardiologie B, hôpital Bichat, Paris.

出版信息

Arch Mal Coeur Vaiss. 1997 Jul;90(7):995-8.

PMID:9339263
Abstract

The authors report the anatomo-clinical features of aortic insufficiency complicating atrophic polychondritis, a rare inflammatory disease affecting mainly cartilaginous tissues. This case illustrates the inflammatory changes of the aortic wall, particularly progressive during this disease, responsible for aortic insufficiency and aneurysmal dilatation of the ascending aorta which required aortic valve replacement and prosthetic replacement of the ascending aorta. Histological analysis showed inflammatory lesions of the aortic wall comparable to the cartilaginous lesions described in this condition and suggesting a common physiopathogenic mechanism.

摘要

作者报告了萎缩性多软骨炎并发主动脉瓣关闭不全的解剖学临床特征,萎缩性多软骨炎是一种主要影响软骨组织的罕见炎症性疾病。该病例说明了主动脉壁的炎症变化,尤其是在这种疾病过程中呈进行性变化,导致主动脉瓣关闭不全和升主动脉瘤样扩张,这需要进行主动脉瓣置换和升主动脉人工血管置换。组织学分析显示主动脉壁的炎症病变与该病中描述的软骨病变相似,提示存在共同的病理生理机制。

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