Yasuda T, Ishihara H, Amano H, Shishido K
Department of Life Science, Faculty of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan.
Biosci Biotechnol Biochem. 1997 Sep;61(9):1587-9. doi: 10.1271/bbb.61.1587.
The Arg-Gly-Asp (RGD) motif-containing fragment of high-molecular-weight cell-adhesion protein MFBA derived from Lentinus edodes caused a significant aggregation of the fragmented hyphal cells of Schizophyllum commune. This fungal cell-aggregation was inhibited by a previous treatment of the cells with the Gly-Arg-Gly-Asp-Ser-Pro peptide, but not with the Gly-Arg-Gly-Glu-Ser-Pro peptide, showing that the RGD motif is essential for the cell-aggregation activity.
来源于香菇的高分子量细胞粘附蛋白MFBA的含精氨酸-甘氨酸-天冬氨酸（RGD）基序片段，可引起裂褶菌破碎菌丝细胞的显著聚集。用甘氨酸-精氨酸-甘氨酸-天冬氨酸-丝氨酸-脯氨酸肽预先处理细胞可抑制这种真菌细胞聚集，但甘氨酸-精氨酸-甘氨酸-谷氨酸-丝氨酸-脯氨酸肽则不能，这表明RGD基序对细胞聚集活性至关重要。
