Miller N S, Ninonuevo F G, Klamen D L, Hoffmann N G, Smith D E
Department of Psychiatry, The University of Illinois at Chicago, 60612-7327, USA.
J Psychoactive Drugs. 1997 Jul-Sep;29(3):239-48. doi: 10.1080/02791072.1997.10400197.
A multi-site, longitudinal study of patients undergoing outpatient alcohol and drug dependence treatment was conducted in private outpatient facilities, consisting of 2,029 subjects from 33 independent programs enrolled in a national addiction treatment outcomes registry. Pretreatment demographic and substance variables, treatment utilization variables, and post-treatment continuum of care variables were examined simultaneously in a multivariate prediction context for association with outcome. Upon admission patients provided history information to treatment staff trained in the collection of data for the evaluation efforts. Trained interviewers conducted consecutive structured interviews prospectively for treatment outcome at six- and 12-month follow-up periods. Multivariate analysis with stepwise multiple regression indicated that, relatively speaking, the most powerful predictors of treatment outcome were posttreatment variables: namely, support group attendance and involvement in a continuing care program. Pretreatment and treatment variables contributed proportionately little to the prediction of outcome. Additional sequential-stage analysis showed that the incremental contribution to prediction by posttreatment attendance at Alcoholics Anonymous and involvement in a treatment program following discharge far exceeded the initial predictive validity of the 14 pretreatment and treatment variables examined. Participation in posttreatment continuing care correlated with statistically significant reductions in job absenteeism, inpatient hospitalizations, and arrest rates. Posttreatment more than pretreatment factors may be decisive in influencing risk for relapse.
在私立门诊机构对接受门诊酒精和药物依赖治疗的患者进行了一项多地点纵向研究,该研究纳入了来自33个独立项目的2029名受试者,这些项目均登记在一个全国成瘾治疗结果登记处。在多变量预测背景下,同时检查治疗前的人口统计学和物质变量、治疗利用变量以及治疗后连续护理变量与结果的关联。入院时,患者向接受过为评估工作收集数据培训的治疗人员提供病史信息。经过培训的访谈员在6个月和12个月的随访期前瞻性地进行连续的结构化访谈以了解治疗结果。逐步多元回归的多变量分析表明,相对而言,治疗结果最有力的预测因素是治疗后变量:即参加支持小组和参与持续护理项目。治疗前和治疗变量对结果预测的贡献相对较小。额外的序贯阶段分析表明,参加戒酒互助会的治疗后出勤率和出院后参与治疗项目对预测的增量贡献远远超过所检查的14个治疗前和治疗变量的初始预测效度。参与治疗后持续护理与旷工率、住院率和逮捕率的统计学显著降低相关。治疗后因素比治疗前因素在影响复发风险方面可能更具决定性。