Yalçin A D, Kaymaz A, Forta H
Department of Neurology, Sişli Etfal Education Hospital, Istanbul, Turkey.
Brain Dev. 1997 Sep;19(6):408-13. doi: 10.1016/s0387-7604(97)00054-5.
Childhood epilepsy with occipital paroxysms (CEOP) is an idiopathic localization-related epilepsy. A typical seizure in CEOP begins with visual symptoms, followed by hemiclonic seizures, complex partial seizures or generalized tonic-clonic seizures. Benign nocturnal childhood occipital epilepsy (BNCOE), characterized by nocturnal seizures with tonic deviation of the eyes followed by vomiting, has the same electroencephalographic features as CEOP. In this study, we report the seizure symptoms and electroencephalographic features of 21 cases with CEOP or BNCOE. Out of these patients, nine had BNCOE, six had CEOP, four had CEOP and BNCOE and the remaining two belonged to the incomplete syndrome because of no paroxysmal discharges in EEG. When the patients with BNCOE awoke from sleep, they had tonic deviation of the eyes and could describe visual symptoms. Patients with CEOP had seizures beginning with visual symptoms followed by loss of consciousness but no generalized convulsions. In three cases, in addition to the occipital spikes, independent centro-temporal spikes were recorded and in another three cases generalized spike-wave discharges were recorded. Such a combination suggests the idiopathic nature of these epilepsies. We concluded that in the diagnosis of CEOP and BNCOE, the seizure symptomatology is important even if the EEG can be considered normal.
儿童枕叶阵发性癫痫（CEOP）是一种特发性局灶性癫痫。CEOP的典型发作始于视觉症状，随后是半侧阵挛发作、复杂部分性发作或全身性强直阵挛发作。良性儿童枕叶夜间癫痫（BNCOE）的特征是夜间发作，伴有眼球强直性偏斜，随后呕吐，其脑电图特征与CEOP相同。在本研究中，我们报告了21例CEOP或BNCOE患者的发作症状和脑电图特征。这些患者中，9例患有BNCOE，6例患有CEOP，4例同时患有CEOP和BNCOE，其余2例因脑电图无阵发性放电而属于不完全综合征。BNCOE患者从睡眠中醒来时，会出现眼球强直性偏斜，并能描述视觉症状。CEOP患者的发作始于视觉症状，随后意识丧失，但无全身性惊厥。3例患者除枕叶棘波外，还记录到独立的中央颞区棘波，另外3例记录到全身性棘慢波放电。这种组合提示了这些癫痫的特发性本质。我们得出结论，在CEOP和BNCOE的诊断中，即使脑电图可被视为正常，发作症状学也很重要。
