Panayiotopoulos C P
Department of Neurology, King Khalid University Hospital, Riyadh, Saudi Arabia.
J Child Neurol. 1989 Jan;4(1):43-9. doi: 10.1177/088307388900400107.
An epileptic syndrome of benign nocturnal childhood occipital epilepsy with excellent prognosis is described. The syndrome is characterized by a clinical ictal triad of nocturnal seizures, tonic deviation of the eyes, and vomiting. There may be marching to involve the head and limbs, ending with a generalized tonic-clonic seizure. Consciousness is usually, but not invariably, disturbed. Infrequent daytime fits may develop one to two years after remission of the nocturnal seizures. Age of onset is usually from 3 to 5 years. Both sexes are involved. There is no family history of epilepsy or migraine. No definite causative factor was detected. The frequency of the seizures is very low with two children having only solitary ones. The interictal electroencephalographic features consist of repetitive occipital spike and slow wave complexes that are induced by closed eyes and darkness and are inhibited by open eyes and fixation with visual cues. It is proposed that this is a new idiopathic age-related-onset syndrome of the localization-related epilepsies.
本文描述了一种预后良好的儿童良性夜间枕叶癫痫综合征。该综合征的临床发作三联征为夜间发作、双眼强直性偏斜和呕吐。发作可能扩展至头部和四肢，最终发展为全身性强直阵挛发作。意识通常会受到干扰，但并非总是如此。夜间发作缓解一至两年后可能会出现不频繁的日间发作。发病年龄通常在3至5岁。男女均可发病。无癫痫或偏头痛家族史。未检测到明确的致病因素。发作频率非常低，两名儿童仅有单次发作。发作间期脑电图特征为重复性枕叶棘波和慢波复合波，闭眼和处于黑暗环境时诱发，睁眼并注视视觉刺激时受到抑制。有人提出这是一种新的与年龄相关的特发性局灶性癫痫综合征。
