Cheng A T, Backer C L, Holinger L D, Dunham M E, Mavroudis C, Gonzalez-Crussi F
Division of Pediatric Otolaryngology, The Children's Memorial Hospital, Chicago, Ill 60614, USA.
Arch Otolaryngol Head Neck Surg. 1997 Oct;123(10):1069-72. doi: 10.1001/archotol.1997.01900100043006.
Pericardial patch tracheoplasty has been used for surgical correction of long-segment congenital tracheal stenosis caused by complete tracheal rings in infants. The case histories of 2 infants with descriptions of the histopathologic changes in their respective tracheas are presented. Complete reepithelialization of the graft site with ciliated pseudostratified columnar epithelium was found, suggesting the likelihood of normal mucociliary flow in the trachea. The pericardial patches were replaced by mature scar tissue in the graft site, establishing a functional tracheal lumen. Wound healing in the trachea is reviewed. Obstruction by exuberant granulation tissue is an ongoing concern. Pericardium continues to be an important option as graft material for tracheal reconstruction in infants with long-segment congenital tracheal stenosis.
心包补片气管成形术已用于手术矫正婴儿因完全气管环导致的长段先天性气管狭窄。本文介绍了2例婴儿的病例史，并描述了其各自气管的组织病理学变化。发现移植部位完全重新上皮化，形成纤毛假复层柱状上皮，提示气管内正常黏液纤毛流动的可能性。心包补片在移植部位被成熟瘢痕组织替代，形成了功能性气管腔。本文还回顾了气管的伤口愈合情况。过度增生的肉芽组织造成的梗阻仍是一个持续存在的问题。对于患有长段先天性气管狭窄的婴儿，心包仍是气管重建移植材料的重要选择。
