Bongrani S, Baldi G, Cucchini F, di Donato M, Visioli O
Acta Radiol Diagn (Stockh). 1979;20(5):769-78. doi: 10.1177/028418517902000509.
A low osmolality contrast medium (Iopamidol) caused less cardiac disturbance on isolated rabbit heart than a high osmolality medium (Urografin). The same effects were induced by glucose solutions iso-osmolal with the two media. After perfusion with Propranolol (1 microgram/ml) and Cimetidine (1 microgram/ml) the observed effect was unaltered.
与高渗性造影剂(泛影葡胺)相比,低渗性造影剂(碘帕醇)对离体兔心脏的心脏干扰较小。与这两种造影剂等渗的葡萄糖溶液也产生了相同的效果。在用普萘洛尔(1微克/毫升)和西咪替丁(1微克/毫升)灌注后,观察到的效果没有改变。