Choudari C P
Division of Gastroenterology, University Medical Center, Indianapolis 64202-5250, USA.
Gastroenterologist. 1997 Sep;5(3):242-6.
Bleeding is the major risk associated with anticoagulation therapy. The gastrointestinal tract is the most common site of bleeding. Anticoagulated patients who present with acute gastrointestinal hemorrhage pose great therapeutic challenges. In patients who experience a life-threatening hemorrhage, difficult decisions must be made regarding reversal of anticoagulation, timing of endoscopy and endoscopic therapy, and when to reinstitute anticoagulation. The current literature on the approach to patients who present with major gastrointestinal bleeding while on anticoagulant therapy is reviewed.
出血是抗凝治疗相关的主要风险。胃肠道是最常见的出血部位。出现急性胃肠道出血的抗凝患者面临巨大的治疗挑战。对于发生危及生命出血的患者,在抗凝逆转、内镜检查及内镜治疗时机以及何时重新开始抗凝方面必须做出艰难决策。本文综述了目前关于接受抗凝治疗时出现严重胃肠道出血患者的处理方法的文献。