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流量调节型和压力依赖性流量泵诱导溶血的体外研究。

In vitro study of hemolysis induced by flow-regulated and pressure-dependent flow pumps.

作者信息

Gille J P, Stahl R L

出版信息

Med Prog Technol. 1976 Apr 30;3(4):169-73.

PMID:934039
Abstract

In vitro experiments showed that a pressure-dependent flow pump which "obeys Starling's law" (with flexible tube stretched on vertical rotor) was less hemolytic than a classical flow-regulated pump (with pump inset occluded between a rotor and a stator). The degree of hemolysis obtained with fresh human blood was higher with blood from chronic respiratory patients than with blood from normal donors. Also, the hemolysis was less with fresh heparinized blood than with stored ACD blood, and less with normal blood than with diluted blood. Comparing hemodialysis pumps with ECC pumps showed that hemolysis tripled with the pressure-dependent flow types and was 30 times higher with the classical pumps.

摘要

体外实验表明,一台“遵循斯塔林定律”的压力依赖性流量泵(柔性管在垂直转子上伸展)比传统的流量调节泵(泵体嵌于转子和定子之间)溶血更少。用新鲜人血获得的溶血程度,慢性呼吸疾病患者的血液比正常供血者的血液更高。此外,新鲜肝素化血液的溶血程度低于储存的ACD血液,正常血液的溶血程度低于稀释血液。将血液透析泵与体外循环泵进行比较表明,压力依赖性流量类型的溶血程度增至三倍,而传统泵的溶血程度则高出30倍。

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