Schädlich P K, Paschen B, Brecht J G
InForMed, Gesselschaft für interdisziplinäre Forschung und Beratung im Gesundheitswesen, Hamburg.
Med Klin (Munich). 1997 Aug 15;92(8):499-504. doi: 10.1007/BF03044920.
The Cardiac Insufficiency Bisoprolol Study (CIBIS) demonstrates that, for patients with heart failure of different etiologies, the administration of the beta(1)-adrenoceptor blocker bisoprolol adjuvant to the standard therapy leads to a significant avoidance of hospital admissions.
The results of the CIBIS were evaluated pharmacoeconomically for the Federal Republic of Germany, and were restricted to direct costs only. The costs of bisoprolol medication and in-patient treatment of heart failure were considered, the latter forming the major part of costs incurred.
Adjunctive therapy with bisoprolol is not only clinically beneficial to the patient with heart failure, but also economically advantageous.
心脏不全比索洛尔研究(CIBIS)表明,对于不同病因的心力衰竭患者,在标准治疗基础上加用β1肾上腺素能受体阻滞剂比索洛尔可显著减少住院次数。
对德国联邦共和国的CIBIS结果进行了药物经济学评估,且仅局限于直接成本。评估了比索洛尔药物治疗和心力衰竭住院治疗的成本,后者构成了所产生成本的主要部分。
比索洛尔辅助治疗不仅对心力衰竭患者具有临床益处,而且在经济上也具有优势。