Moskowitz M, Milbrath J, Gartside P, Zermeno A, Mandel D
N Engl J Med. 1976 Jul 29;295(5):249-52. doi: 10.1056/NEJM197607292950504.
In a study of thermograms of 42 patients with Stage 1 or smaller carcinomas of the breast, 44 confounding cases and 64 randomly selected subjects being screened, we found that the ability of expert thermographers to identify the patients with carcinoma correctly (true positive = 0.238) varied little from the ability of untrained readers (true positive = 0.301). Furthermore, in the expert group, the indexes of suspicion were so high (0.436) and the true-positive levels were so relatively low (0.238, P = 0.0005) that thermography may well have a very limited role as a screening or pre-screening modality for the detection of minimal or Stage 1 breast cancers.
在一项针对42例患有1期或更小乳腺癌的患者、44例混淆病例以及64例随机挑选接受筛查的受试者的热像图研究中，我们发现，专业热像图分析人员正确识别癌症患者的能力（真阳性率 = 0.238）与未经训练的读者的能力（真阳性率 = 0.301）相差无几。此外，在专业人员组中，可疑指数非常高（0.436），而真阳性水平相对较低（0.238，P = 0.0005），以至于热像图作为一种检测微小或1期乳腺癌的筛查或预筛查手段，其作用很可能非常有限。
