Mason O, Claridge G, Clark K
Department of Clinical Psychology, University of Wales, UK.
Int J Psychophysiol. 1997 Sep;27(2):137-46. doi: 10.1016/s0167-8760(97)00057-3.
The relationships between several indices of psychosis proneness and bilateral electrodermal orienting were examined in a large group of normal subjects and a heterogeneous group of schizophrenic patients. In the normal group, the Cognitive Disorganisation scale was characterised by shorter latencies and more irregular patterns of responding that may indicate greater disinhibitory processing in the regulation of attentional mechanisms. The Unusual Experiences scale and paranoia (both measures of positive or 'active' schizotypy) were associated with a predominance of left hemisphere influences in normal female controls. High Introvertive Anhedonia scores predicted non-responding status in schizophrenic patients and hypo-responsivity in normal controls in support of some previous studies. Overall the results support the specificity and validity of different measures of psychosis proneness and the utility of psychophysiological investigation beyond the psychotic disorders themselves.
在一大组正常受试者和一组异质性精神分裂症患者中，研究了几种精神病易感性指标与双侧皮肤电定向之间的关系。在正常组中，认知紊乱量表的特点是潜伏期较短，反应模式更不规则，这可能表明在注意力机制调节中存在更大的去抑制性加工。异常体验量表和偏执狂（均为阳性或“活跃”分裂型人格的测量指标）在正常女性对照组中与左半球影响占主导地位有关。高内向性快感缺失得分预示着精神分裂症患者无反应状态以及正常对照组反应低下，这支持了一些先前的研究。总体而言，结果支持了不同精神病易感性测量指标的特异性和有效性，以及心理生理学研究在精神病性障碍本身之外的效用。
