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特纳综合征患者身高、身高增长速度和体重的参考值。瑞典生长激素治疗研究组

Reference values for height, height velocity and weight in Turner's syndrome. Swedish Study Group for GH treatment.

作者信息

Rongen-Westerlaken C, Corel L, van den Broeck J, Massa G, Karlberg J, Albertsson-Wikland K, Naeraa R W, Wit J M

机构信息

Department of Paediatrics, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.

出版信息

Acta Paediatr. 1997 Sep;86(9):937-42. doi: 10.1111/j.1651-2227.1997.tb15174.x.

DOI:10.1111/j.1651-2227.1997.tb15174.x
PMID:9343271
Abstract

As Northern Europeans are currently the tallest people in the world, specific growth charts for girls with Turner's Syndrome from this area are needed. Based on height and weight measurements from 598 girls with Turner's Syndrome (372 from the Netherlands, 108 from Denmark, 118 from Sweden) not treated with growth-promoting substances and without signs of spontaneous puberty, we constructed growth charts for height-for-age, height-velocity-for-age, weight-for-age, weight-for-height and Body Mass Index for age. Reference tables and regression equations for mean and standard deviation are provided allowing calculation of Standard Deviation Scores. The height and height velocity curves show a low birth length, gradual deviation from the normal percentile curves without pubertal growth spurt, and a prolonged growth until the early 20s. Mean adult height was 146.9 +/- 7.8 cm. Mean weight-for-age was lower than in normal reference children but height-adjusted weight was higher, except in infancy and early childhood. Further studies are required on the factors influencing the weight-height relationship in Turner's Syndrome.

摘要

由于北欧人目前是世界上最高的人群,因此需要该地区特纳综合征女孩的特定生长图表。基于598名未接受促生长物质治疗且无自发青春期迹象的特纳综合征女孩(372名来自荷兰,108名来自丹麦,118名来自瑞典)的身高和体重测量数据,我们构建了年龄别身高、年龄别身高增长速度、年龄别体重、身高别体重和年龄别身体质量指数的生长图表。提供了均值和标准差的参考表及回归方程,用于计算标准差分数。身高和身高增长速度曲线显示出生时身长较低,逐渐偏离正常百分位数曲线且无青春期生长突增,生长持续到20岁出头。成年女性平均身高为146.9 +/- 7.8厘米。年龄别平均体重低于正常参考儿童,但身高校正体重较高,婴儿期和幼儿期除外。需要进一步研究影响特纳综合征体重与身高关系的因素。

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