色胺抑制血清素的再摄取。
Inhibition of the reuptake of serotonin by tryptoline.
作者信息
Rommelspacher H, Bade P, Coper H, Kossmehl G
出版信息
Naunyn Schmiedebergs Arch Pharmacol. 1976;292(1):93-5. doi: 10.1007/BF00506495.
PMID:934360
Abstract
Tryptoline, a metabolite of tryptamine, competitively inhibits serotonin accumulation in nuclei-free homogenate of rat "forebrains". After intraventricular injection the drug elicits an increase of serotonin levels in the same part of the brain whereas the monoamine oxidase activity is not altered.
摘要
色胺酮，色胺的一种代谢产物，可竞争性抑制大鼠“前脑”无细胞核匀浆中5-羟色胺的蓄积。脑室内注射该药物后，可使脑同一部位的5-羟色胺水平升高，而单胺氧化酶活性未发生改变。
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