Albano A, Catapano F, Consoli G, Saltalamacchia G
Minerva Med. 1976 Apr 21;67(19):1255-62.
Continuous infusion with isoproterenol (mean dose 2 mug/min) was carried out for periods of a few hours to a few days in 22 patients recurrent Adams-Stokes syncope. In all cases, an improvement leading to or in the direction of physiological cardio-circulatory conditions was noted. Undesired side-effects foreseeable as the result of beta-adrenergic stimulation were not observed. Isoproterenol is more active than metaproterenol and is to be preferred on this account. It is indicated in Adams-Stokes crises due to conduction disturbances when pacemakers cannot or should not be fitted, or as a prelude to their application.
对22例反复发作阿-斯综合征晕厥的患者持续输注异丙肾上腺素(平均剂量2微克/分钟),持续数小时至数天。在所有病例中,均观察到病情改善,趋向或达到生理心循环状态。未观察到因β-肾上腺素能刺激而可预见的不良副作用。异丙肾上腺素比间羟异丙肾上腺素更有效,因此更值得选用。在因传导障碍导致阿-斯综合征发作且无法或不应安装起搏器时,或作为安装起搏器的前奏时,可使用异丙肾上腺素。