Vaccarello L, Apte S M, Diaz P T, Lewandowski G S, Copeland L J
Division of Gynecologic Oncology, Arthur G. James Cancer Hospital, Ohio State University, Columbus 43210, USA.
Gynecol Oncol. 1997 Oct;67(1):111-4. doi: 10.1006/gyno.1997.4830.
A patient with respiratory failure from metastatic choriocarcinoma was treated with mechanical ventilation while receiving chemotherapy with etoposide, methotrexate, actinomycin D, cyclophosphamide, and vincristine. The patient recovered from respiratory failure with the assistance of standard mechanical ventilation using low tidal volumes. The patient has sustained clinical remission with normal respiratory function. Mechanical ventilation with low tidal volumes and a pressure-targeted approach should be considered in the patient who develops early respiratory failure from metastatic choriocarcinoma.
一名因转移性绒毛膜癌导致呼吸衰竭的患者在接受依托泊苷、甲氨蝶呤、放线菌素D、环磷酰胺和长春新碱化疗的同时接受了机械通气治疗。该患者在使用低潮气量的标准机械通气辅助下从呼吸衰竭中康复。患者目前处于持续临床缓解状态，呼吸功能正常。对于因转移性绒毛膜癌早期出现呼吸衰竭的患者，应考虑采用低潮气量和压力目标导向的机械通气方法。
