酸中毒、局部麻醉药与新生儿
Acidosis, local anesthetics, and the newborn.
作者信息
Brown W U, Bell G C, Alper M H
出版信息
Obstet Gynecol. 1976 Jul;48(1):27-30.
PMID:934571
Abstract
Four newborn infants were studied following maternal epidural block with lidocaine or mepivacaine. Each of these neonates, born with a pH of 7.23 or below in the umbilical vein blood, showed an elevated fetal-to-maternal concentration ratio, a possible manifestation of ion trapping of a weak base.
摘要
对4例在母亲接受利多卡因或甲哌卡因硬膜外阻滞术后的新生儿进行了研究。这些新生儿脐静脉血pH值均在7.23及以下，每例新生儿的胎儿与母体浓度比均升高，这可能是弱碱离子捕获的一种表现。
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