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Anti-tumor necrosis factor alpha therapy of rheumatoid arthritis. Mechanism of action.

作者信息

Feldmann M, Brennan F, Paleolog E, Taylor P, Maini R N

机构信息

The Mathilda & Terrence Kennedy Institute of Rheumatology, Hammersmith, London, UK.

出版信息

Eur Cytokine Netw. 1997 Sep;8(3):297-300.

PMID:9346366
Abstract
摘要

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Anti-tumor necrosis factor alpha therapy of rheumatoid arthritis. Mechanism of action.类风湿关节炎的抗肿瘤坏死因子α治疗。作用机制。
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[Immunotherapy in rheumatoid arthritis; current status].[类风湿关节炎的免疫疗法;现状]
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Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis.类风湿关节炎抗TNF-α治疗后细胞因子、细胞因子抑制剂及急性期蛋白的调节
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The role of cytokines in the pathogenesis of rheumatoid arthritis.细胞因子在类风湿关节炎发病机制中的作用。
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Selective immunosuppression of tumour necrosis factor-alpha in rheumatoid arthritis.
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引用本文的文献

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The intensity of joint pain in relation to changes in serum TNFα during therapy with anti-TNFα inhibitors.治疗中抗 TNFα 抑制剂对血清 TNFα 变化与关节疼痛强度的关系。
Inflammopharmacology. 2019 Aug;27(4):679-683. doi: 10.1007/s10787-019-00564-x. Epub 2019 Jan 24.
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Cytokine and chemokine receptor profile of peripheral blood mononuclear cells during treatment with infliximab in patients with active rheumatoid arthritis.英夫利昔单抗治疗活动期类风湿关节炎患者过程中外周血单个核细胞的细胞因子和趋化因子受体谱
Ann Rheum Dis. 2004 Jun;63(6):681-7. doi: 10.1136/ard.2003.008599.
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Humanized mice as a model for rheumatoid arthritis.
人源化小鼠作为类风湿性关节炎的模型。
Arthritis Res. 2002;4 Suppl 3(Suppl 3):S133-40. doi: 10.1186/ar580. Epub 2002 May 9.
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Effects of treatment with a fully human anti-tumour necrosis factor alpha monoclonal antibody on the local and systemic homeostasis of interleukin 1 and TNFalpha in patients with rheumatoid arthritis.全人源抗肿瘤坏死因子α单克隆抗体治疗对类风湿关节炎患者白细胞介素1和肿瘤坏死因子α局部及全身稳态的影响
Ann Rheum Dis. 2001 Jul;60(7):660-9. doi: 10.1136/ard.60.7.660.
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Interindividual and intra-articular variation of proinflammatory cytokines in patients with rheumatoid arthritis: potential implications for treatment.类风湿关节炎患者促炎细胞因子的个体间和关节内变异:对治疗的潜在影响。
Ann Rheum Dis. 2000 Jun;59(6):439-47. doi: 10.1136/ard.59.6.439.
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PEGylated recombinant human soluble tumour necrosis factor receptor type I (r-Hu-sTNF-RI): novel high affinity TNF receptor designed for chronic inflammatory diseases.聚乙二醇化重组人可溶性肿瘤坏死因子受体I型(r-Hu-sTNF-RI):专为慢性炎症性疾病设计的新型高亲和力肿瘤坏死因子受体
Ann Rheum Dis. 1999 Nov;58 Suppl 1(Suppl 1):I73-81. doi: 10.1136/ard.58.2008.i73.