Carson K, Washington M K, Treem W R, Clavien P A, Hunt C M
Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Liver Transpl Surg. 1997 Mar;3(2):174-6. doi: 10.1002/lt.500030211.
A 42-year-old white man with morbid obesity and hypertriglyceridemia was noted to have nonalcoholic steatohepatitis (NASH) at the time of a laparoscopic cholecystectomy for presumed gallstone pancreatitis. His postoperative course was complicated by a 50-kg weight loss and continued right upper quadrant pain. Repeat liver biopsy revealed NASH with accompanying micronodular cirrhosis. Due to progressive fatigue, he underwent an orthotopic liver transplantation complicated by a 36-kg weight gain. Sixteen months posttransplantation, a liver biopsy revealed the recurrence of NASH. Screening for defects in fatty acid oxidation proved negative.
一名42岁的白人男性，患有病态肥胖和高甘油三酯血症，在因疑似胆结石性胰腺炎行腹腔镜胆囊切除术时被诊断为非酒精性脂肪性肝炎（NASH）。他的术后病程因体重减轻50公斤和右上腹持续疼痛而复杂化。重复肝脏活检显示为NASH并伴有小结节性肝硬化。由于进行性疲劳，他接受了原位肝移植，术后体重增加了36公斤。肝移植后16个月，肝脏活检显示NASH复发。脂肪酸氧化缺陷筛查结果为阴性。
