Antony S J, Patel A, Leonard J
Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
J Natl Med Assoc. 1997 Oct;89(10):694-5.
The treatment of non-acquired immunodeficiency syndrome (AIDS) cryptococcal meningitis has not been well defined as yet. The current recommendation is amphotericin B with or without flucytosine. However, due to the many side effects of these drugs, fluconazole is becoming an attractive alternative in patients who cannot tolerate amphotericin B and flucytosine. This case study demonstrates the successful use of fluconazole in a patient with underlying diabetes mellitus and cryptococcal meningitis.
非获得性免疫缺陷综合征（AIDS）相关隐球菌性脑膜炎的治疗方法目前尚未明确界定。目前的推荐治疗方案是使用两性霉素B，可联合或不联合氟胞嘧啶。然而，由于这些药物存在诸多副作用，对于无法耐受两性霉素B和氟胞嘧啶的患者，氟康唑正成为一种有吸引力的替代药物。本病例研究展示了氟康唑在一名患有基础糖尿病和隐球菌性脑膜炎患者中的成功应用。
