Ciernik I F, Gerster J C, Burckhardt P
Département de médecine interne et service de rhumatologie, Centre hospitalier universitaire vaudois, Lausanne, Switzerland.
Clin Rheumatol. 1997 Sep;16(5):477-9. doi: 10.1007/BF02238941.
Pneumococcal arthritis generally presents as non-destructive monoarthritis, although some underlying metabolic disorders such as liver failure and diabetes have been suggested to represent a risk factor for severe joint disease. Here we report a case of destructive pneumococcal arthritis of the left hip joint in a patient suffering from chronic renal failure treated with hemodialysis for ten years. Inspite of effective anti-pneumococcal antibiotic treatment, the patient with preexisting renal osteopathy and a mild osteoarthritis continued to suffer from severe and disabling pain of the left hip. This case demonstrates that pneumococcal joint infection in patients with underlying uremic bone disease can lead to quick deterioration of the affected joint.
肺炎球菌性关节炎通常表现为非破坏性单关节炎，尽管有研究表明，一些潜在的代谢紊乱，如肝功能衰竭和糖尿病，是严重关节疾病的危险因素。本文报告一例接受血液透析治疗十年的慢性肾衰竭患者发生左髋关节破坏性肺炎球菌性关节炎的病例。尽管进行了有效的抗肺炎球菌抗生素治疗，但该患者原有肾性骨病和轻度骨关节炎，左髋仍持续遭受严重且致残性疼痛。该病例表明，患有潜在尿毒症性骨病的患者发生肺炎球菌关节感染可导致受影响关节迅速恶化。
