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自体脂肪垫移植置换内侧半月板:在绵羊身上的实验研究

Medial meniscus replacement by a fat pad autograft. An experimental study in sheep.

作者信息

Kohn D, Rudert M, Wirth C J, Plitz W, Reiss G, Maschek H

机构信息

Orthopädische Universitätsklinik, Homburg/Saar, Germany.

出版信息

Int Orthop. 1997;21(4):232-8. doi: 10.1007/s002640050157.

DOI:10.1007/s002640050157
PMID:9349959
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3617697/
Abstract

The medial meniscus in 15 sheep was replaced by a pediculated infrapatellar fat pad graft and resulted in the development of a macroscopically meniscus-like structure within 6 months. Five additional sheep with a meniscectomy were controls. Degenerative changes in the fat pad autograft were visible after one year. Osteoarthritis of the weightbearing medial compartment was detected after 6 months. A temporary protective effect on the cartilage could be attributed to the autograft, but the long term results indicated that this was not permanent. Fat is not suitable as a meniscal substitute.

摘要

对15只绵羊的内侧半月板进行带蒂髌下脂肪垫移植替代,结果在6个月内形成了宏观上类似半月板的结构。另外5只接受半月板切除术的绵羊作为对照。1年后可见脂肪垫自体移植物出现退行性改变。6个月后检测到负重内侧间室的骨关节炎。自体移植物对软骨有暂时的保护作用,但长期结果表明这种保护不是永久性的。脂肪不适合作为半月板替代物。

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