Markov V V, Bezverkhaia T P
Probl Endokrinol (Mosk). 1976 May-Jun;22(3):41-4.
The rate of cortizol secretion was determined in 5 healthy persons and 18 patients suffering from thyrotoxicosis by dilution of isotopic label by the mean specific radioactivity of tetrahydrocortizol and tetrahydrocortisone excreted with the urine. There was revealed a close direct dependence of the adrenal gland activation on decompensation of the disease and a reverse dependence on the duration of thyrotoxicosis. The rate of cortizol secretion had a tendency to reduction and normalization in medicinal compensation of thyrotoxicosis.
通过尿中排泄的四氢皮质醇和四氢可的松的平均比放射性对同位素标记进行稀释，测定了5名健康人和18名甲状腺毒症患者的皮质醇分泌率。结果显示，肾上腺激活与疾病失代偿密切相关，与甲状腺毒症持续时间呈负相关。在甲状腺毒症的药物代偿过程中，皮质醇分泌率有降低并趋于正常的趋势。
