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环孢素相关的可逆性后部白质脑病:磁共振成像

Cyclosporine-related reversible posterior leukoencephalopathy: MRI.

作者信息

Jarosz J M, Howlett D C, Cox T C, Bingham J B

机构信息

Dept. of Neuroimaging, King's College Hospital, London, UK.

出版信息

Neuroradiology. 1997 Oct;39(10):711-5. doi: 10.1007/s002340050492.

Abstract

Three patients aged 48, 11 and 40 years, two of whom were recent recipients of renal transplants and one of a bone marrow transplant, developed seizures, with cortical blindness in two cases. All were immunosuppressed with cyclosporine and were hypertensive at the onset of symptoms. MRI showed predominantly posterior signal changes in all three cases. The abnormalities were more conspicuous on fast FLAIR images than on conventional T2-weighted spin-echo images.

摘要

三名患者年龄分别为48岁、11岁和40岁,其中两人近期接受了肾移植,一人接受了骨髓移植,他们均出现了癫痫发作,其中两例伴有皮质盲。所有患者均使用环孢素进行免疫抑制,症状发作时均患有高血压。磁共振成像(MRI)显示,所有三例患者主要表现为后部信号改变。这些异常在快速液体衰减反转恢复(FLAIR)图像上比在传统的T2加权自旋回波图像上更为明显。

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