• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

苏格兰早老性阿尔茨海默病和血管性痴呆治疗病例的死亡证明。

Death certification in treated cases of presenile Alzheimer's disease and vascular dementia in Scotland.

作者信息

Thomas B M, Starr J M, Whalley L J

机构信息

Department of Mental Health, University of Aberdeen, UK.

出版信息

Age Ageing. 1997 Sep;26(5):401-6. doi: 10.1093/ageing/26.5.401.

DOI:10.1093/ageing/26.5.401
PMID:9351485
Abstract

INTRODUCTION

although death certification data are commonly used in dementia epidemiology, their reliability has been questioned.

METHODS

death certificates were available from the Registrar General for Scotland for all patients with Alzheimer's disease/presenile dementia (AD PSD) or vascular dementia (VaD) who had died in Scotland up until 31 December 1994. Primary (immediate and underlying) and contributory causes of death were noted as well as place of death. Occupations of male patients were obtained from death certificates or from case notes and classified according to the Standard Occupational Classification. Bronchopneumonia was considered a non-specific cause of death and specific causes of death were classified as: cardiac disease, dementia, cerebrovascular disease, neoplasms, other vascular diseases and other diseases. Place of death was recorded as psychiatric hospital, district general hospital, nursing home or private residence.

RESULTS

death certificates of 398 people who had been treated for AD PSD and 348 who had been treated for VaD were identified. Bronchopneumonia was the most common immediate cause of death in the AD PSD group (70.9%) but less so for the VaD group (51.7%). For both groups place of death was associated with significant differences in pneumonia being reported as the immediate cause of death as well as specific underlying and contributory causes of death. Dementia was recorded for 90.5% of AD PSD patients but for only 49.7% of the VaD group.

CONCLUSIONS

Scottish death certificate data significantly underestimate the prevalence of presenile VaD. Changes in patterns of institutional care may affect dementia rates estimated from death certificate data.

摘要

引言

尽管死亡证明数据在痴呆症流行病学中普遍使用,但其可靠性一直受到质疑。

方法

可从苏格兰总登记官处获取截至1994年12月31日在苏格兰死亡的所有阿尔茨海默病/早老性痴呆(AD/PSD)或血管性痴呆(VaD)患者的死亡证明。记录主要(直接和根本)死因及促成死因以及死亡地点。男性患者的职业从死亡证明或病历中获取,并根据标准职业分类进行分类。支气管肺炎被视为非特异性死因,具体死因分类为:心脏病、痴呆症、脑血管疾病、肿瘤、其他血管疾病和其他疾病。死亡地点记录为精神病院、地区综合医院、疗养院或私人住宅。

结果

确定了398名接受过AD/PSD治疗患者和348名接受过VaD治疗患者的死亡证明。支气管肺炎是AD/PSD组最常见的直接死因(70.9%),但在VaD组中比例较低(51.7%)。两组的死亡地点在报告肺炎为直接死因以及具体根本和促成死因方面均存在显著差异。90.5%的AD/PSD患者记录有痴呆症,而VaD组仅为49.7%。

结论

苏格兰死亡证明数据显著低估了早老性VaD的患病率。机构护理模式的变化可能会影响根据死亡证明数据估算的痴呆症发病率。

相似文献

1
Death certification in treated cases of presenile Alzheimer's disease and vascular dementia in Scotland.苏格兰早老性阿尔茨海默病和血管性痴呆治疗病例的死亡证明。
Age Ageing. 1997 Sep;26(5):401-6. doi: 10.1093/ageing/26.5.401.
2
Familial or sporadic clusters of presenile dementia in Scotland: I. Parental causes of death in Alzheimer and vascular presenile dementias.苏格兰早老性痴呆的家族性或散发性聚集:I. 阿尔茨海默病和血管性早老性痴呆患者父母的死因
Psychiatr Genet. 1997 Winter;7(4):141-6.
3
Causes of Death According to Death Certificates in Individuals with Dementia: A Cohort from the Swedish Dementia Registry.根据痴呆症患者死亡证明得出的死因:来自瑞典痴呆症登记处的队列研究
J Am Geriatr Soc. 2016 Nov;64(11):e137-e142. doi: 10.1111/jgs.14421. Epub 2016 Nov 1.
4
Death certification after a diagnosis of presenile dementia.早老性痴呆诊断后的死亡证明
J Epidemiol Community Health. 1993 Aug;47(4):293-7. doi: 10.1136/jech.47.4.293.
5
Epidemiology of presenile Alzheimer's disease in Scotland (1974-88) II. Exposures to possible risk factors.
Br J Psychiatry. 1995 Dec;167(6):732-8. doi: 10.1192/bjp.167.6.732.
6
Cause of death in demented and non-demented elderly inpatients; an autopsy study of 308 cases.痴呆与非痴呆老年住院患者的死因;308例尸检研究
J Alzheimers Dis. 2005 Sep;8(1):57-62. doi: 10.3233/jad-2005-8107.
7
Reporting of dementia on death certificates: a community study.死亡证明上痴呆症的报告:一项社区研究。
J Am Geriatr Soc. 1999 Jul;47(7):842-9. doi: 10.1111/j.1532-5415.1999.tb03842.x.
8
The 'natural' endpoint of dementia: death from cachexia or dehydration following palliative care?痴呆症的“自然”终点:姑息治疗后因恶病质或脱水而死亡?
Int J Geriatr Psychiatry. 2007 Apr;22(4):350-5. doi: 10.1002/gps.1680.
9
Reporting of clinically diagnosed dementia on death certificates: retrospective cohort study.死亡证明上临床诊断痴呆症的报告:回顾性队列研究。
Age Ageing. 2016 Sep;45(5):668-73. doi: 10.1093/ageing/afw077. Epub 2016 May 4.
10
Cause of death in patients with dementia disorders.痴呆症患者的死因
Eur J Neurol. 2009 Apr;16(4):488-92. doi: 10.1111/j.1468-1331.2008.02503.x.

引用本文的文献

1
Childhood intelligence in relation to major causes of death in 68 year follow-up: prospective population study.68年随访中儿童智力与主要死因的关系:前瞻性人群研究
BMJ. 2017 Jun 28;357:j2708. doi: 10.1136/bmj.j2708.
2
Reporting of clinically diagnosed dementia on death certificates: retrospective cohort study.死亡证明上临床诊断痴呆症的报告:回顾性队列研究。
Age Ageing. 2016 Sep;45(5):668-73. doi: 10.1093/ageing/afw077. Epub 2016 May 4.
3
Cerebral inflammation is an underlying mechanism of early death in Alzheimer's disease: a 13-year cause-specific multivariate mortality study.
脑炎症是阿尔茨海默病患者早逝的潜在机制:一项长达 13 年的特定病因多变量死亡率研究。
Alzheimers Res Ther. 2014 Jul 7;6(4):41. doi: 10.1186/alzrt271. eCollection 2014.
4
Antibiotics and mortality in patients with lower respiratory infection and advanced dementia.抗生素与下呼吸道感染合并晚期痴呆患者的死亡率。
J Am Med Dir Assoc. 2012 Feb;13(2):156-61. doi: 10.1016/j.jamda.2010.07.001. Epub 2010 Oct 8.
5
Which aspects of subjectively reported quality of life are important in predicting mortality beyond known risk factors? The Lothian Birth Cohort 1921 Study.哪些主观报告的生活质量方面对于预测已知风险因素之外的死亡率很重要?洛锡安出生队列 1921 年研究。
Qual Life Res. 2011 Feb;20(1):81-90. doi: 10.1007/s11136-010-9718-1. Epub 2010 Jul 27.
6
Survival and comfort after treatment of pneumonia in advanced dementia.晚期痴呆患者肺炎治疗后的生存情况与舒适度
Arch Intern Med. 2010 Jul 12;170(13):1102-7. doi: 10.1001/archinternmed.2010.181.
7
Predictors of mortality in nursing home residents with advanced dementia.养老院中患有晚期痴呆症的居民的死亡预测因素。
Am J Alzheimers Dis Other Demen. 2010 Aug;25(5):439-45. doi: 10.1177/1533317510370955. Epub 2010 Jul 2.
8
Age-related changes in memory and fluid reasoning in a sample of healthy old people.健康老年人样本中记忆和流畅推理的年龄相关变化。
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2010 Jan;17(1):55-70. doi: 10.1080/13825580903009071. Epub 2009 Jul 1.
9
Agreement between nosologist and cardiovascular health study review of deaths: implications of coding differences.疾病分类学家与心血管健康研究死亡审查之间的一致性:编码差异的影响
J Am Geriatr Soc. 2009 Jan;57(1):133-9. doi: 10.1111/j.1532-5415.2008.02056.x. Epub 2008 Nov 12.
10
Vital records and dementia.生命记录与痴呆症
Neuroepidemiology. 2009;32(1):70-1. doi: 10.1159/000170909. Epub 2008 Nov 12.