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苏格兰早老性阿尔茨海默病和血管性痴呆治疗病例的死亡证明。

Death certification in treated cases of presenile Alzheimer's disease and vascular dementia in Scotland.

作者信息

Thomas B M, Starr J M, Whalley L J

机构信息

Department of Mental Health, University of Aberdeen, UK.

出版信息

Age Ageing. 1997 Sep;26(5):401-6. doi: 10.1093/ageing/26.5.401.

Abstract

INTRODUCTION

although death certification data are commonly used in dementia epidemiology, their reliability has been questioned.

METHODS

death certificates were available from the Registrar General for Scotland for all patients with Alzheimer's disease/presenile dementia (AD PSD) or vascular dementia (VaD) who had died in Scotland up until 31 December 1994. Primary (immediate and underlying) and contributory causes of death were noted as well as place of death. Occupations of male patients were obtained from death certificates or from case notes and classified according to the Standard Occupational Classification. Bronchopneumonia was considered a non-specific cause of death and specific causes of death were classified as: cardiac disease, dementia, cerebrovascular disease, neoplasms, other vascular diseases and other diseases. Place of death was recorded as psychiatric hospital, district general hospital, nursing home or private residence.

RESULTS

death certificates of 398 people who had been treated for AD PSD and 348 who had been treated for VaD were identified. Bronchopneumonia was the most common immediate cause of death in the AD PSD group (70.9%) but less so for the VaD group (51.7%). For both groups place of death was associated with significant differences in pneumonia being reported as the immediate cause of death as well as specific underlying and contributory causes of death. Dementia was recorded for 90.5% of AD PSD patients but for only 49.7% of the VaD group.

CONCLUSIONS

Scottish death certificate data significantly underestimate the prevalence of presenile VaD. Changes in patterns of institutional care may affect dementia rates estimated from death certificate data.

摘要

引言

尽管死亡证明数据在痴呆症流行病学中普遍使用,但其可靠性一直受到质疑。

方法

可从苏格兰总登记官处获取截至1994年12月31日在苏格兰死亡的所有阿尔茨海默病/早老性痴呆(AD/PSD)或血管性痴呆(VaD)患者的死亡证明。记录主要(直接和根本)死因及促成死因以及死亡地点。男性患者的职业从死亡证明或病历中获取,并根据标准职业分类进行分类。支气管肺炎被视为非特异性死因,具体死因分类为:心脏病、痴呆症、脑血管疾病、肿瘤、其他血管疾病和其他疾病。死亡地点记录为精神病院、地区综合医院、疗养院或私人住宅。

结果

确定了398名接受过AD/PSD治疗患者和348名接受过VaD治疗患者的死亡证明。支气管肺炎是AD/PSD组最常见的直接死因(70.9%),但在VaD组中比例较低(51.7%)。两组的死亡地点在报告肺炎为直接死因以及具体根本和促成死因方面均存在显著差异。90.5%的AD/PSD患者记录有痴呆症,而VaD组仅为49.7%。

结论

苏格兰死亡证明数据显著低估了早老性VaD的患病率。机构护理模式的变化可能会影响根据死亡证明数据估算的痴呆症发病率。

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